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KMID : 1157520120080010057
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International Journal of Clinical Preventive Dentistry
2012 Volume.8 No. 1 p.57 ~ p.63
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The Effects of Dentifrice Mixed with Potassium Nitrate, Cetylpyridinium Chloride and Zea Mays L. Extractin Preventing Dentin Hypersensitivity and Gum Diseases
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Hwang Kyung-Sook
Lee Sun-Kyoung
Kim Seong-Hoon
Hwang Jee-hyun
Kwon Ha-Jeong
Chae Sang-Kyun
Sung Young-Eun
Kim Chan-Ho
Lee John-Hwan
Park Yong-Duk
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Abstract
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Objective: The purpose of this clinical study was to test the efficacy and safety of dentifrice which has effects of reducing dental hypersensitivity (sodium mono fluordie phosphate), anti bacterial and anti immflamatory effects.
Methods: 91 Korean adult subjects have participated and scaling was given right before the initial oral examination to set the oral condition same amongst the subjects. After the run-in period over two weeks, subjects brushed only with distributed dentifrice for three month of time period. The final data sets from dentifrice B and dentifrice C were compared to the control group to compare the improvements using mixtures with sodium mono fluoride phosphate, cetylpyridium chloride, and Zea mays L. unsaponifiable extraction in different concentration.
Results: Over three months period, both test group 1(B) and test group 2(C) each showed 34.98% and 27.95% improvements in reduction of dentin hypersensitivity. Both test group 1(B) and test group 2(B) showed 39.22% and 31.5% statistically significant improvements in plaque index (p<0.05). Test group 1(B) and test group 2(C) each showed 21.15% and 30.95% improvements in gingival index (p<0.05).
Conclusion: The ingredients of sodium mono-fluoride phosphate to strengthen enamel, KNO3 to reduce dentin hypersensitivity, CPC and Zea Mays L. unsaponifiable extraction to prevent gingivitis were indeed effective in protecting sensitive gingiva. No side effects were found throughout the whole body including the oral cavity of the subjects.
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KEYWORD
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dentifrice, hypersensitivity, potassium nitrate, Zea Mays L.
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